Learn more about Fostemsavir

Antibody-directed cell cytotoxicity as a driver for cell death in uninfected CD4 T cells.

Consequences of persistently low CD4 T cells in HIV-1

CD4 T cells increase observed in BRIGHTE Study

gp120 persists despite viral suppression

Depletion of CD4 T cells occurs continues with viral suppression

What are the implications of low CD4 T cell count

gp120 is one of the drivers in HIV associated inflammation

Fostemsavir binds to gp120 that is attached to HIV-1 and soluble

Study design of the Phase III BRIGHTE study

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