The Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection (Pediatric Guidelines) address the diagnosis of HIV infection in infants and children and the use of antiretroviral therapy (ART) in children and adolescents with HIV. The Pediatric Guidelines also include recommendations for managing adverse events that are associated with the use of antiretroviral (ARV) drugs in children and a detailed review of the safety, efficacy, and pharmacokinetics (PKs) of ARV agents in children.
For adolescents ages 13 and up, the Adult & Adolescent Treatment Guidelines provide guidance on the use of ARVs and their management. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV
Additional information on the management of Opportunistic Infections in children and adolescents are available here: Updates to the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Exposed and HIV-Infected Children | NIH
Adherence to ART is a principal determinant of virologic suppression.4,5 Suboptimal adherence may include missed or late doses, treatment interruptions and discontinuations, and subtherapeutic or partial dosing.6,7 One of the major barriers to adherence among the pediatric population is the ability to swallow pills. This resource addresses the topic of adherence in children living with HIV.
HIV Drug Resistance
This resource describes the implications of HIV drug resistance and strategies for identifying and preventing drug resistance.