Fostemsavir Characteristics

Fostemsavir^▼characteristics

Learn more about the key attributes and core benefits of RUKOBIA based on the Phase III BRIGHTE data.

Story of Fostemsavir

The development of fostemsvir has been many years in the making. Here we describe its journey from conception to development. phase clinicals, and EMA and FDA approval

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Mechanism of Action

Entry of the HIV into a target cell occurs through a process of 3 main steps. HIV entry inhibitors are varied in their point of action. Here we detail where the different entry inhibitors act and if they are pre attachment of post attachment. Fostemsavir has a new mechanism of action that is able tobind onto gp120, to prevent HIV attachment and entry.

The Three Stages of HIV Cell Entry

Entry of the HIV-1 virus into a target cell occurs through 3 main steps

HIV-1 cell entry and lifecycle

An overview of the HIV-1 lifecycle, from cell entry to the production of new virions

Fostemsavir’s Mechanism of Action

Fostemsavir has a unique mechanism of action that is able to bind viral gp120 preventing HIV-1 attachment and entry

Elimination of HIV Following Fostemsavir Action

After fostemsavir blocks HIV-1 attachment to target cells, the virus of informacion tor products remains in the extracellular space where it can be eliminated by the and host immune responses

240wk BRIGHTE Study Results

An overview of outcomes at 240 Week from the BRIGHTE Phase Ill study of fostemsavir in heavily treatment experienced patients.

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Building an Antiretroviral OBR with Fostemsavir in a clinic setting

An overview of important considerations for building an optimized background therapy with fostemsavir in a clinic environment.

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fostemsavir ▼ prescribing information

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