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Joe Mrus, MD

Executive Medical Director
North America Medical Affairs


Dr. Joseph Mrus is an accomplished leader at ViiV Healthcare, bringing with him significant expertise in medical affairs, clinical research, clinical practice, and health outcomes. Active in the HIV arena for over twenty years, he has contributed in many ways to improved care and treatment for people living with HIV.

Current Role

As ViiV’s Executive Medical Director for North America Medical Affairs since 2016, Joe built and now oversees the US Medical Team responsible for developing research initiatives and creating medical and patient education and support programs for ViiV’s marketed and investigational products. He also develops and implements the medical strategy for ViiV therapies, and supports the commercial organization with input, clinical review, education, and training. In addition, he leads and moderates advisory boards and conducts a myriad of other activities aimed at supporting ViiV products and ensuring integrity from a medical perspective.


Joe came to ViiV with key global medical affairs and clinical affairs leadership experience gained at Janssen Pharmaceutical, where, in his most recent role as Medical Leader for Global Public Health, he led the clinical team and clinical development activities for global public health products, including a long-acting HIV entity. In other positions at Janssen, he held medical leadership roles in the infectious disease and virology treatment areas as the US Medical Director for HIV products and the Global Medical Affairs Leader supporting the infectious disease portfolio, including HIV and hepatitis C. Prior to joining industry, Joe was an academic clinician and researcher during twelve years at the University of Cincinnati Medical Center and its affiliates. He provided general care for inpatient and outpatient pediatric and adult patients, and HIV specialty care for adults, children, and pregnant women, as well as, consulted and lectured regionally on pediatric and perinatal HIV. His academic career included teaching as Associate Professor of Clinical Medicine, research in HIV and hepatitis C, and numerous professional activities including clinical, scientific, and administrative roles; and he has published over 50 original articles.


Joe earned his MD in 1994 from the University of Texas Health Science Center at Houston, and completed a MS in Epidemiology in 1999 from Harvard School of Public Health. He also holds a MS in Biomedical Engineering from the University of Texas and a BS in Mechanical Engineering from GMI Engineering and Management Institute (now Kettering University) in Flint, MI. His postdoctoral training includes a medical residency in Internal Medicine and Pediatrics at the University of Cincinnati Affiliated Hospitals, and participation in the Program in Clinical Effectiveness (jointly with Brigham and Women’s Hospital, Massachusetts General Hospital, and Harvard Medical School and School of Public Health). In addition, Joe was a Fellow in Outcomes Research at University of Cincinnati Medical Center.

Personal Interests

Joe lives in Cary, North Carolina with his wife and 3 children. He enjoys participating with his family in sports, activities in the outdoors, and travel.

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